A piperazine salt form of estrone 3-sulfate; inhibits OAT1B1 selectively over OAT1B3 (IC50s = 0.06 and 19.32 µM

Estropipate – 5 mg

Brand:
Cayman
CAS:
7280-37-7
Storage:
-20
UN-No:
Non-Hazardous - /

Estropipate is a piperazine salt form of estrone 3-sulfate (Item No. 20513), which is an inactive endogenous steroid that is converted into estrone (Item No. 10006485) in vivo.{32192} Estropipate is also an inhibitor of organic anion transport polypeptide 1B1 (OATP1B1) that is selective for OAT1B1 over OAT1B3 (IC50s = 0.06 and 19.3 µM, respectively).{41286} Formulations containing estropipate have been used in the treatment of menopausal symptoms and for the prevention of osteoporosis in high risk populations.  

 

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SKU: 23806 - 5 mg Category:

Description

A piperazine salt form of estrone 3-sulfate; inhibits OAT1B1 selectively over OAT1B3 (IC50s = 0.06 and 19.32 µM, respectively)

Formal name: 3-(sulfooxy)-estra-1,3,5(10)-trien-17-one, compd. with piperazine

Synonyms:  Piperazine Estrone Sulfate

Molecular weight: 436.6

CAS: 7280-37-7

Purity: ≥98%

Formulation: A solid

Product Type|Biochemicals|Lipids|Sterol Lipids||Product Type|Biochemicals|Transporter & Exchanger Modulators||Research Area|Endocrinology & Metabolism|Bone Growth & Remodeling||Research Area|Endocrinology & Metabolism|Hormones & Receptors|Estrogens & Progestins

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