A synthetic estrogen; stimulates proliferation of estrogen-dependent MCF-7 breast cancer cells in vitro from 0.16-20 μM; lacks ER binding activity (IC50s = >100 μM for ERα and ERβ); has been used in the synthesis of various estrogen receptor modulators

Estrone 3-methyl ether – 10 g

Brand:
Cayman
CAS:
1624-62-0
Storage:
-20
UN-No:
Non-Hazardous - /

Estrone 3-methyl ether is a synthetic estrogen and derivative of estrone (Item No. 10006485).{51105} It stimulates proliferation of estrogen-dependent MCF-7 breast cancer cells in vitro when used at concentrations ranging from 0.16 to 20 μM but lacks estrogen receptor (ER) binding activity (IC50s = >100 μM for ERα and ERβ). Estrone 3-methyl ether has been used in the synthesis of various estrogen receptor modulators.{51106}  

 

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SKU: 27978 - 10 g Category:

Description

A synthetic estrogen; stimulates proliferation of estrogen-dependent MCF-7 breast cancer cells in vitro from 0.16-20 μM; lacks ER binding activity (IC50s = >100 μM for ERα and ERβ); has been used in the synthesis of various estrogen receptor modulators

Formal name: 3-methoxy-estra-1,3,5(10)-trien-17-one

Synonyms:  (+)-Estrone methyl ether|3-O-methyl Estrone|NSC 88911

Molecular weight: 284.4

CAS: 1624-62-0

Purity: ≥90%

Formulation: A crystalline solid

Product Type|Biochemicals|Lipids|Sterol Lipids||Research Area|Endocrinology & Metabolism|Hormones & Receptors|Estrogens & Progestins

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