Estrone is one of the three naturally occurring estrogens

Estrone – 1 g

Brand:
Cayman
CAS:
53-16-7
Storage:
-20
UN-No:
Non-Hazardous - /

Estrone is one of the three naturally occurring estrogens, the others being estradiol and estriol.{9611} Estrone is synthesized from androstenedione by the aromatase enzyme system in the ovaries and placenta, and is also synthesized from estradiol by 17-hydroxy steroid dehydrogenase in the liver.{9611,8343} Serum concentrations of estrone in premenopausal women fluctuate according to the menstrual cycle and becomes the most predominant estrogen in postmenopausal women.{9611} The binding affinities of estrone to the estrogen receptors α and β are approximately 60% and 37% relative to estradiol.{9611}  

 

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SKU: 10006485 - 1 g Category:

Description

Estrone is one of the three naturally occurring estrogens, the others being estradiol and estriol.{9611} Estrone is synthesized from androstenedione by the aromatase enzyme system in the ovaries and placenta, and is also synthesized from estradiol by 17-hydroxy steroid dehydrogenase in the liver.{9611,8343} Serum concentrations of estrone in premenopausal women fluctuate according to the menstrual cycle and becomes the most predominant estrogen in postmenopausal women.{9611} The binding affinities of estrone to the estrogen receptors α and β (ERα and ERβ) are approximately 60% and 37% relative to estradiol.{9611}

Formal name: 3-hydroxy-estra-1,3,5(10)-trien-17-one

Synonyms:  E1

Molecular weight: 270.4

CAS: 53-16-7

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Lipids|Sterol Lipids||Product Type|Biochemicals|Receptor Pharmacology||Research Area|Endocrinology & Metabolism|Hormones & Receptors|Estrogens & Progestins||Research Area|Endocrinology & Metabolism|Reproductive Biology

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