A synthetic estrogen; reduces estrogen-depletion induced spikes in basal tail temperature in ovariectomized wild-type

Estradiol Cypionate – 1 g

Brand:
Cayman
CAS:
313-06-4
Storage:
-20
UN-No:
Non-Hazardous - /

Estradiol cypionate is a synthetic estrogen and an ester derivative of 17β-estradiol (Item No. 10006315).{54282,54283,54284} In vivo, estradiol cypionate (0.1 mg/kg per day) reduces estrogen depletion-induced spikes in basal tail temperature in ovariectomized wild-type, estrogen receptor α knockout (ERα-/-), and ERβ-/- mice.{54282} It increases the rate of pregnancy in cows induced to ovulate small dominant follicles with gonadotropin-releasing hormone (GnRH).{54283} Estradiol cypionate also reduces edema and articular joint neutrophil infiltration in an ovariectomized mouse model of zymosan-induced arthritis.{54284} Formulations containing estradiol cypionate have been used in the treatment of menopausal symptoms and low estrogen levels.  

 

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SKU: 31105 - 1 g Category:

Description

A synthetic estrogen; reduces estrogen-depletion induced spikes in basal tail temperature in ovariectomized wild-type, ERα-/-, and ERβ-/- mice at 0.1 mg/kg per day; increases the rate of pregnancy in cows induced to ovulate small dominant follicles; reduces edema and articular joint neutrophil infiltration in an ovariectomized mouse model of zymosan-induced arthritis

Formal name: estra-1,3,5(10)-triene-3,17β-diol 17-cyclopentanepropanoate

Synonyms:  Estradiol 17-Cypionate|Estradiol 17β-Cyclopentanepropionate|NSC 3354

Molecular weight: 396.6

CAS: 313-06-4

Purity: ≥98%

Formulation: A solid

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