An estradiol analog that binds to ERα with IC50 values in the range of 22-28 nM

Estradiol Benzoate – 5 g

Brand:
Cayman
CAS:
50-50-0
Storage:
-20
UN-No:
Non-Hazardous - /

Estrogens direct the development of the female genotype in embryogenesis and at puberty. Estradiol is the major estrogen secreted by the premenopausal ovary.{8342,8343} Estradiol benzoate is an estradiol analog which contains a benzyl ester at the C-3 position. It is often used in combination with a progestin to induce estrus in domestic livestock.{13000} Estradiol benzoate binds to the human and murine estrogen receptor α (ERα), and chicken ER with IC50 values in the range of 22-28 nM.{12991} This reflects a 6-10 fold reduction in binding affinity compared to estradiol.{12991}  

 

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SKU: 10006487 - 5 g Category:

Description

An estradiol analog that binds to ERα with IC50 values in the range of 22-28 nM

Formal name: estra-1,3,5(10)-triene-3,17β-diol 3-benzoate

Synonyms:  17β-Estradiol 3-Benzoate|17β-Oestradiol Benzoate|E2 Benzoate|β-Estradiol Benzoate

Molecular weight: 376.5

CAS: 50-50-0

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Lipids|Sterol Lipids||Product Type|Biochemicals|Receptor Pharmacology||Research Area|Endocrinology & Metabolism|Hormones & Receptors|Estrogens & Progestins||Research Area|Endocrinology & Metabolism|Reproductive Biology

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