The (S)-enantiomer of omeprazole

Esomeprazole Magnesium – 10 mg

Brand:
Cayman
CAS:
161973-10-0
Storage:
-20
UN-No:
Non-Hazardous - /

Esomeprazole, the (S)-enantiomer of omeprazole (Item No. 14880), is a selective inhibitor of the gastric H+/K+ ATPase.{18249} It is highly effective at inhibiting gastric acid secretion and demonstrates lower first-pass hepatic metabolism and slower plasma clearance, resulting in increased bioavailability compared to omeprazole.{18249,28643} Esomeprazole is predominantly metabolized by the cytochrome P450 (CYP) isomer CYP3A4.{18249}  

 

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Description

The (S)-enantiomer of omeprazole, a selective inhibitor of the gastric H+/K+ ATPase that demonstrates increased bioavailability compared to omeprazole

Formal name: (T-4)-bis[6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl-κO]-1H-benzimidazolato-κN3]-magnesium

Synonyms:  (S)-Omeprazole

Molecular weight: 713.1

CAS: 161973-10-0

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Small Molecule Inhibitors|ATPases||Research Area|Toxicology|Drug Metabolism|Cytochrome P450

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