A selective serotonin reuptake inhibitor (IC50 = 2.1 nM in rat synaptosomes); has no effect on norepinephrine or dopamine reuptake; more potent than the racemic mixture citalopram or (R)-citalopram (IC50s = 3.9 and 280 nM

Escitalopram – 10 mg

Brand:
Cayman
CAS:
128196-01-0
Storage:
-20
UN-No:
De Minimis - 1170 / 3

Escitalopram ((S)-citalopram) is a selective serotonin reuptake inhibitor.{38120} It blocks serotonin reuptake in rat brain synaptosomes (IC50 = 2.1 nM) without affecting norepinephrine or dopamine reuptake.{38121} Escitalopram is more potent than the racemic mixture citalopram (Item No. 14572) or (R)-citalopram (IC50s = 3.9 and 280 nM, respectively).{38122} Formulations containing escitalopram have been used to treat anxiety in depressive disorders, post-traumatic stress disorder (PTSD), obsessive compulsive disorder (OCD) and panic disorders.{38120}  

 

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Description

A selective serotonin reuptake inhibitor (IC50 = 2.1 nM in rat synaptosomes); has no effect on norepinephrine or dopamine reuptake; more potent than the racemic mixture citalopram or (R)-citalopram (IC50s = 3.9 and 280 nM, respectively),

Formal name: (1S)-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancarbonitrile

Synonyms:  (S)-Citalopram

Molecular weight: 324.4

CAS: 128196-01-0

Purity: ≥98%

Formulation: A solution in ethanol

Product Type|Biochemicals|Transporter & Exchanger Modulators||Research Area|Neuroscience|Behavioral Neuroscience|Anxiety||Research Area|Neuroscience|Behavioral Neuroscience|Depression

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