A flavonoid with antioxidant activity; inhibits lipid peroxidation in a cell-free assay at 10 µM; decreases TBARS in rat plasma at 75 µmol/kg; prevents acute exercise-induced increases in TBARS

Eriocitrin – 1 mg

Brand:
Cayman
CAS:
13463-28-0
Storage:
-20
UN-No:
Non-Hazardous - /

Eriocitrin is a flavonoid originally isolated from lemon peel that has antioxidant and enzyme inhibitory activity.{47241,47242,47243,47244,47245} Eriocitrin inhibits lipid peroxidation in a cell-free assay when used at a concentration of 10 µM and enhances the effect of α-tocopherol (Item No. 25985) on lipid peroxidation.{47242} It also decreases thiobarbituric acid reactive substances (TBARS) in rat plasma when administered at a dose of 75 µmol/kg, indicating a reduction in lipid peroxidation.{47243} Eriocitrin prevents acute exercise-induced increases in TBARS, Nε-(hexanoyl)lysine (HEL), o,o-dityrosine (DT), and nitrotyrosine (NT; Item No. 89540) in rat liver when administered at a dose of 600 mg/kg prior to exercise.{47244} It is also an inhibitor of monoamine oxidase A (MAO-A) and MAO-B (IC50s = 86.5 and 164 µM, respectively, for human recombinant receptors).{47245}  

 

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SKU: 25838 - 1 mg Category:

Description

A flavonoid with antioxidant activity; inhibits lipid peroxidation in a cell-free assay at 10 µM; decreases TBARS in rat plasma at 75 µmol/kg; prevents acute exercise-induced increases in TBARS, HEL, DT, and NT in rat liver at 600 mg/kg prior to exercise; an inhibitor of MAO-A and MAO-B (IC50s = 86.5 and 164 µM, respectively)

Formal name: (2S)-7-[[6-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2-(3,4-dihydroxyphenyl)-2,3-dihydro-5-hydroxy-4H-1-benzopyran-4-one

Synonyms:  Eriodictioside|Eriodictyol 7-O-rutinoside

Molecular weight: 596.5

CAS: 13463-28-0

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Ox Stress Reagents|Antioxidants||Product Type|Biochemicals|Small Molecule Inhibitors||Research Area|Oxidative Stress & Reactive Species|Antioxidant Activity||Research Area|Oxidative Stress & Reactive Species|Lipid Peroxidation

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