An equine estrogen; has no effect on eNOS activity or expression and does not increase production of NO; is metabolized to 4-hydroxyequilenin in MCF-7 and MDA-MB-231 breast cancer cells

Equilenin – 500 µg

Brand:
Cayman
CAS:
517-09-9
Storage:
-20
UN-No:
Non-Hazardous - /

Equilenin is an equine estrogen found in the urine of pregnant mares.{40235} Unlike naturally occurring human estrogens, equilenin has no effect on nitric oxide synthase (eNOS) activity or expression and does not increase production of nitric oxide (NO). It is metabolized to 4-hydroxyequilenin, a carcinogenic compound that induces transformation of C3H 10T½ murine fibroblasts.{40236} Formulations containing equilenin conjugates have been widely used as hormone replacement therapies for post-menopausal women.  

 

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Description

An equine estrogen; has no effect on eNOS activity or expression and does not increase production of NO; is metabolized to 4-hydroxyequilenin in MCF-7 and MDA-MB-231 breast cancer cells

Formal name: 3-hydroxy-estra-1,3,5,7,9-pentaen-17-one

Synonyms:  (+)-Equilenin|d-Equilenin|NSC 9901

Molecular weight: 266.3

CAS: 517-09-9

Purity: ≥98%

Formulation: A solid

Product Type|Biochemicals|Lipids|Sterol Lipids||Research Area|Endocrinology & Metabolism|Hormones & Receptors|Estrogens & Progestins||Research Area|Endocrinology & Metabolism|Reproductive Biology

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