(-)-Epinephrine – 25 g

Brand:
Cayman
CAS:
51-43-4
Storage:
-20
UN-No:
Excepted Quantity - 2811 / 6.1

(-)-Epinephrine is a natural neurotransmitter that is released from the adrenal medulla and activates adrenoceptors (Kis = 15, 735, and 3,970 nM for α1A-, β2-, and β1-adrenergic receptors, respectively).{26355,25395,30131} Through these receptors, (-)-epinephrine may induce either contraction or relaxation of vascular smooth muscle, depending on adrenoceptor subtype expression.{30131} Receptor-mediated actions of (-)-epinephrine are also relevant to blocking anaphylaxis, reversing cardiac arrest, and reducing bleeding in clinical trials.{30133,30132,30134}  

 

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Description

A natural neurotransmitter that is activates adrenoceptors (Kis = 15, 735, and 3,970 nM for α1A-, β2-, and β1-adrenergic receptors, respectively); may induce either contraction or relaxation of vascular smooth muscle, depending on adrenoceptor subtype expression


Formal name: 4-[(1R)-1-hydroxy-2-(methylamino)ethyl]-1,2-benzenediol

Synonyms:  Adrenaline|NSC 62786

Molecular weight: 183.2

CAS: 51-43-4

Purity: ≥95%

Formulation: A crystalline solid


Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Cardiovascular System|Vasculature|Smooth Muscle Cells||Research Area|Cardiovascular System|Vasculature|Vasoconstriction||Research Area|Cardiovascular System|Vasculature|Vasodilation||Research Area|Immunology & Inflammation|Allergy||Research Area|Neuroscience