A flavonoid glycoside; scavenges DPPH radicals in a cell-free assay (IC50 = 107.9 µM); increases proliferation of UMR-106 osteoblasts by 24.9 and 36.3% at 10 and 100 µM

Epimedin B – 10 mg

Brand:
Cayman
CAS:
110623-73-9
Storage:
-20
UN-No:
Non-Hazardous - /

Epimedin B is a flavonoid glycoside that has been found in E. koreanum and has antioxidant, anti-osteoporotic, and anti-inflammatory activities.{52255,52256,52257,52258,48447} It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; Item No. 14805) radicals in a cell-free assay (IC50 = 107.9 µM).{52256} Epimedin B increases proliferation of UMR-106 osteoblasts by 24.9 and 36.3% when used at concentrations of 10 and 100 µM, respectively.{52257} It prevents osteoporosis induced by prednisolone (Item No. 20866) in zebrafish when used at a concentration of 1 µM.{52258} Epimedin B inhibits ear edema induced by phorbol 12-myristate 13-acetate (TPA; Item No. 10008014) in mice (ED50 = 114 nmol/ear).{48447}  

 

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SKU: 29694 - 10 mg Category:

Description

A flavonoid glycoside; scavenges DPPH radicals in a cell-free assay (IC50 = 107.9 µM); increases proliferation of UMR-106 osteoblasts by 24.9 and 36.3% at 10 and 100 µM, respectively; prevents prednisolone-induced osteoporosis in zebrafish at 1 µM; inhibits TPA-induced ear edema in mice (ED50 = 114 nmol/ear)

Formal name: 3-[(6-deoxy-2-O-β-D-xylopyranosyl-α-L-mannopyranosyl)oxy]-7-(β-D-glucopyranosyloxy)-5-hydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one

Synonyms: 

Molecular weight: 808.8

CAS: 110623-73-9

Purity: ≥98%

Formulation: A crystalline solid

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