A 2R

(-)-Epicatechin – 10 mg

Brand:
Cayman
CAS:
490-46-0
Storage:
-20
UN-No:
Non-Hazardous - /

Catechin is a polyphenolic flavonoid that has been isolated from a variety of natural sources including tea leaves, grape seeds, and the wood and bark of trees such as acacia and mahogany.{7686,23117} Catechin is a more potent antioxidant than ascorbate or α-tocopherol in certain in vitro lipid peroxidation assays.{7582} (−)-Epicatechin is a 2R,3R stereoisomer of catechin. Like catechin, (−)-epicatechin is a powerful antioxidant.{23115} It inhibits cyclooxygenase 1 (IC50 = 3.2 μM).{15205} Also, at 100 µM, (−)-epicatechin induces apoptosis in human adenocarcinoma PC-9 cells and stimulates the inhibition of tumor necrosis factor-α release from BALB-c/3T3 cells treated with epigallocatechin gallate.{23116}  

 

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SKU: 11807 - 10 mg Category:

Description

A 2R,3R stereoisomer of catechin; a powerful antioxidant; inhibits COX-1 (IC50 = 3.2 μM); at 100 µM, induces apoptosis in human adenocarcinoma PC-9 cells and stimulates the inhibition of TNF-α release from BALB-c/3T3 cells treated with epigallocatechin gallate

Formal name: 2R-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3R,5,7-triol

Synonyms:  epi-Catechin|NSC 81161

Molecular weight: 290.3

CAS: 490-46-0

Purity: ≥90%

Formulation: A crystalline solid

Product Type|Biochemicals|Natural Products|Flavonoids||Product Type|Biochemicals|Natural Products|Polyphenols||Product Type|Biochemicals|Ox Stress Reagents|Antioxidants||Product Type|Biochemicals|Small Molecule Inhibitors|Cyclooxygenases||Research Area|Cancer|Cell Death|Apoptosis||Research Area|Oxidative Stress & Reactive Species|Antioxidant Activity

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