A metabolite of progesterone and an inactive isomer of allopregnanolone

Epiallopregnanolone – 5 mg

Brand:
Cayman
CAS:
567-01-1
Storage:
-20
UN-No:
Non-Hazardous - /

Neuroactive steroids (widely known as neurosteroids), including progesterone (Item No. 15876) and several of its metabolites, have been shown to mediate some of their physiological effects though a modulatory site on GABAA receptors.{17638} Epiallopregnanolone is a metabolite of progesterone and a 3β-isomer of allopregnanolone (Item No. 16930), which has been shown to enhance GABA neurotransmission.{27521,26687} Epiallopregnanolone is inactive as a GABAA receptor modulator and is used as a control substance to examine GABA neurotransmission.{29963}  

 

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Description

A metabolite of progesterone and an inactive isomer of allopregnanolone, a positive modulator of GABAA receptors

Formal name: (3β,5α)-3,21-dihydroxy-pregnan-20-one

Synonyms:  3β,21-dihydroxy-5α-Pregnan-20-one|3β,5α-Tetrahydrodeoxycorticosterone|3β,5α-Tetrahydroprogesterone|5α-Pregnan-20-one

Molecular weight: 334.5

CAS: 567-01-1

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Ion Channel Modulation||Product Type|Biochemicals|Lipids|Sterol Lipids||Research Area|Endocrinology & Metabolism|Hormones & Receptors|Estrogens & Progestins||Research Area|Neuroscience

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