Description
The biological effects of prostaglandin E2 (PGE2) are mediated through interaction with four distinct membrane-bound G-protein coupled EP receptors: EP1, EP2, EP3, and EP4.{6742,9114} As a result of splice variation, the EP3 receptor can be expressed as multiple isoforms that differ in the length and sequence of their C-terminal tails.{9114,3180} The signal transduction mechanism varies depending on the isoform being expressed, implicating the importance of the C-terminal region of the receptor for coupling to G-proteins.{9114,3180} The EP3 receptor is expressed in a variety of tissues with highest levels in kidney, pancreas, and uterus.{3180,1610,3179}
Synonyms: PGE2 Receptor 3|Prostaglandin E2 Receptor 3
Immunogen: Synthetic peptide from an internal region of human EP3 receptor
Formulation: 500 µl of peptide affinity-purified antibody
Isotype:
Applications: ICC, IHC, and WB
Origin: Animal/Rabbit
Stability: 365 days
Application|Immunocytochemistry||Application|Immunohistochemistry||Application|Western Blot||Product Type|Antibodies|Polyclonal Antibodies||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway
