One of four major analogs in the enniatin complex that has been shown to moderately inhibit ACAT activity in rat liver microsomes (IC50 = 22 µM); demonstrates anthelmintic properties against N. brasiliensis

Enniatin A – 2.5 mg

Brand:
Cayman
CAS:
2503-13-1
Storage:
-20
UN-No:
De Minimis - 3462 / 6.1

Enniatins are cyclohexadepsipeptides commonly isolated from fungi that are known to have antibiotic properties and to induce apoptosis in several cancer lines.{24952} Many function as ionophores, forming pores in cellular membranes to allow selective ion transport.{24952,24954} Enniatin A is one of four major analogs in the enniatin complex (Item No. 9002040). It has been shown to moderately inhibit acyl-CoA:cholesterol acyltranferase activity in rat liver microsomes with an IC50 value of 22 µM.{24950} Enniatin A also demonstrates anthelmintic properties against N. brasiliensis, T. spiralis, and H. spumosa.{24952}  

 

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Description

One of four major analogs in the enniatin complex that has been shown to moderately inhibit ACAT activity in rat liver microsomes (IC50 = 22 µM); demonstrates anthelmintic properties against N. brasiliensis, T. spiralis, and H. spumosa

Formal name: cyclo[(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-isoleucyl-(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-isoleucyl-(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-isoleucyl]

Synonyms: 

Molecular weight: 681.9

CAS: 2503-13-1

Purity: ≥99%

Formulation: A solid

Product Type|Biochemicals|Antibiotics|Polypeptides||Product Type|Biochemicals|Ion Channel Modulation||Product Type|Biochemicals|Natural Products||Product Type|Biochemicals|Peptides||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Parasitic Diseases

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