Description
A selective c-Met inhibitor (IC50 = 3 nM) that inhibits c-Met phosphorylation and downstream signaling in various cancer cell lines (IC50s = 6-9 nM) and at 5-15 mg/kg regresses tumors in mouse xenograft models
Formal name: 3-[1,6-dihydro-1-[[3-[5-[(1-methyl-4-piperidinyl)methoxy]-2-pyrimidinyl]phenyl]methyl]-6-oxo-3-pyridazinyl]-benzonitrile
Synonyms: MSC2156119|Tepotinib
Molecular weight: 492.6
CAS: 1100598-32-0
Purity: ≥98%
Formulation: A crystalline solid
Product Type|Biochemicals|Kinase Inhibitors|Other Receptor Tyrosine Kinases||Product Type|Biochemicals|Small Molecule Inhibitors|Kinases||Research Area|Cancer|Cell Signaling
