Description
A glycoside with diverse biological activities; protects against Aβ (25-35)-induced axonal and dendritic atrophies in primary rat cortical neurons; reduces macrophage infiltration, pannus formation, cartilage damage, bone erosion, and the production of TNF-α and IL-6 in a mouse model of collagen-induced arthritis at 15, 30, and 60 mg/kg; increases insulin sensitivity and reduces pancreatic α- and β-cell death in db/db mice; increases latency to enter the dark chamber in a passive avoidance test and hippocampal GSH levels and decreases errors in the Y-maze test and hippocampal MDA levels in a mouse model of sleep deprivation-induced stress at 10 and 50 mg/kg
Formal name: [(1R,3aR,4S,6aS)-tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl]bis(2,6-dimethoxy-4,1-phenylene)bis-β-D-glucopyranoside
Synonyms: Syringin E
Molecular weight: 742.7
CAS: 39432-56-9
Purity: ≥95%
Formulation: A crystalline solid