An AChE inhibitor (Kis = 0.2 - 0.4 µM) that is known to prevent the breakdown of the neurotransmitter acetylcholine by binding specifically to its catalytic site; used as part of a battery of pharmacological tests to confirm a diagnoses of myasthenia gravis

Edrophonium (chloride) – 500 mg

Brand:
Cayman
CAS:
116-38-1
Storage:
-20
UN-No:
Non-Hazardous - /

Edrophonium (chloride) is an acetylcholinesterase (AChE) inhibitor that is known to prevent the breakdown of the neurotransmitter acetylcholine by binding specifically to its catalytic site.{19397} It has been shown to inhibit AChE activity in human red blood cells, purified calf forebrain, and purified octopus brain with Ki values of 0.2, 0.2, and 0.4 µM, respectively.{25818} Edrophonium is often used as part of a battery of pharmacological tests to confirm a diagnosis of the autoimmune neuromuscular junction disorder, myasthenia gravis.{25819}  

 

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Description

An AChE inhibitor (Kis = 0.2 – 0.4 µM) that is known to prevent the breakdown of the neurotransmitter acetylcholine by binding specifically to its catalytic site; used as part of a battery of pharmacological tests to confirm a diagnoses of myasthenia gravis

Formal name: N-ethyl-3-hydroxy-N,N-dimethyl-benzenaminium, monochloride

Synonyms:  Enlon®|Tensilon®

Molecular weight: 201.7

CAS: 116-38-1

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Small Molecule Inhibitors|Acetylcholine Turnover||Research Area|Immunology & Inflammation|Autoimmunity||Research Area|Neuroscience

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