A PPARγ agonist; activates PPARγ in a reporter assay using CV-1 cells expressing murine PPARγ2 from 0.1-1 μM; increases [3H]2-deoxyglucose transport in the presence and absence of insulin and increases glycogen synthesis in the presence of insulin in soleus muscle strips isolated from obese rats at 1

Edaglitazone – 5 mg

Brand:
Cayman
CAS:
213411-83-7
Storage:
-20
UN-No:
Non-Hazardous - /

Edaglitazone is an agonist of peroxisome proliferator-activated receptor γ (PPARγ).{47216} It activates PPARγ in a reporter assay using CV-1 cells expressing murine PPARγ2 when used at concentrations ranging from 0.1 to 1 μM. Edaglitazone (1, 5, and 25 μM) increases [3H]2-deoxyglucose transport in the presence and absence of insulin and increases glycogen synthesis in the presence of insulin in soleus muscle strips isolated from obese rats.  

 

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Description

A PPARγ agonist; activates PPARγ in a reporter assay using CV-1 cells expressing murine PPARγ2 from 0.1-1 μM; increases [3H]2-deoxyglucose transport in the presence and absence of insulin and increases glycogen synthesis in the presence of insulin in soleus muscle strips isolated from obese rats at 1, 5, and 25 μM

Formal name: 5-[[4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]benzo[b]thien-7-yl]methyl]-2,4-thiazolidinedione

Synonyms:  BM 13.1258

Molecular weight: 464.6

CAS: 213411-83-7

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Endocrinology & Metabolism|Hormones & Receptors|PPARs||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Diabetes

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