Cayman’s DUB Activity Assay Kit facilitates the rapid

DUB Activity Assay Kit – 96 wells

Brand:
Cayman
Storage:
-80

Deubiquitinating enzymes (DUBs) remove ubiquitin from modified proteins in order to recycle ubiquitin attached to inappropriate targets, to remove and disassemble polyubiquitin chains, and to process proteins prior to their degradation by the proteasome.{26595} They have been implicated in a number of human diseases and thus, are attractive targets for potential therapeutic intervention via the development of suitable inhibitors and modulators.{26597,26595} Cayman’s DUB Activity Assay Kit facilitates the rapid, robust measurement of deubiquitinating enzyme activity in vitro. The kit utilizes a high purity, fluorogenic substrate (ubiquitin-AMC) together with suitable calibration standards and controls for the accurate and sensitive assessment of DUB activity. Continuous kinetic or end-point assays can be performed in a 96-well plate format for multi-sample analysis.  

 

Available on backorder

Add to quotes
SKU: 701490 - 96 wells Category:

Description

Cayman’s DUB Activity Assay Kit facilitates the rapid, robust measurement of deubiquitinating enzyme activity in vitro. The kit utilizes a high purity, fluorogenic substrate (ubiquitin-AMC) together with suitable calibration standards and controls for the accurate and sensitive assessment of DUB activity. Continuous kinetic or end-point assays can be performed in a 96-well plate format for multi-sample analysis. Each kit contains sufficient material for one full 96-well plate assay set-up to be run. Ubiquitin-AMC is not a suitable substrate for all DUBs. Compatibility must be determined by the end user.

Formulation:

Formal name:

Synonyms:  Deubiquitinating Enzyme

Host:

Imunogen:

Applications: 

Clone:

Purity:

Origin:

Application|High-Throughput Screening||Product Type|Assay Kits|Enzyme Activity||Product Type|Assay Kits|Fluorometric Assays||Product Type|Assay Kits|Inhibitor Screening Assays||Research Area|Cell Biology|Proteolysis|Ubiquitin/Proteasome System

Related products