A butyrophenone that acts as an antagonist at dopamine receptors (Kis = 0.25 and 0.84 nM at human D2 and D4); less potently inhibits the human voltage-gated potassium channel (IC50 = 32 nM)

Droperidol – 100 mg

Brand:
Cayman
CAS:
548-73-2
Storage:
-20
UN-No:
Non-Hazardous - /

Droperidol is a butyrophenone that acts as an antagonist at dopamine receptors (Kis = 0.25 and 0.84 nM at human D2 and D4).{30677} It less potently inhibits the human voltage-gated potassium channel (IC50 = 32 nM).{30675} Droperidol has been shown to provide relief from acute migraines and prevent nausea and vomiting in clinical trials.{30676,30674}  

 

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Description

A butyrophenone that acts as an antagonist at dopamine receptors (Kis = 0.25 and 0.84 nM at human D2 and D4); less potently inhibits the human voltage-gated potassium channel (IC50 = 32 nM)

Formal name: 1-​[1-​[4-​(4-​fluorophenyl)​-​4-​oxobutyl]​-​1,​2,​3,​6-​tetrahydro-​4-​pyridinyl]​-​1,​3-​dihydro-2H-​benzimidazol-​2-​one

Synonyms:  NSC 169874

Molecular weight: 379.4

CAS: 548-73-2

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Ion Channel Modulation|Blockers||Product Type|Biochemicals|Receptor Pharmacology|Antagonists||Research Area|Neuroscience|Pain Research

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