Description
The DP1 receptor is one of two receptor isoforms for prostaglandin D2 (PGD2), a major cyclooxygenase metabolite of arachidonic acid. As a G-protein coupled receptor (GPCR), the receptor primarily couples to Gs to increase cAMP, but also transiently increases Ca2+, apparently through the cAMP pathway.{11488} DP1 receptor mRNA has been detected in various tissues and cells including brain, spleen, lung, bone marrow, stomach, skin, and mast cells,{3175, 3128,9114} however little is know about its protein localization due to its low level of expression. Cayman’s DP1 receptor polyclonal antibody detects the protein by western blot in samples such as cerebral cortex, hippocampus, and HT-29 cells, a colorectal cancer cell line shown to express this receptor.{12254}
Synonyms: PGD2 Receptor|Prostaglandin D2 Receptor
Immunogen: Synthetic peptide from the N-terminal region of mouse protein
Formulation: 500 µl of peptide-affinity purified antibody
Isotype:
Applications: IF and WB
Origin: Animal/Rabbit
Stability: 365 days
Application|Immunofluorescence||Application|Western Blot||Product Type|Antibodies|Polyclonal Antibodies||Research Area|Immunology & Inflammation|Innate Immunity||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway
