A broad-spectrum antibiotic; is active against Gram-negative and Gram-positive bacteria

Doripenem – 10 mg

Brand:
Cayman
CAS:
148016-81-3
Storage:
-20
UN-No:
Non-Hazardous - /

Doripenem is a broad-spectrum antibiotic in the β-lactam subclass known as carbapenems.{27718,27720} It is active against Gram-negative and Gram-positive bacteria, including S. aureus, S. pneumoniae, E. coli, and K. pneumoniae (MICs = 0.03-0.06, 0.016-0.06, P. aeruginosa respiratory tract infection when administered at a dose of 100 mg/kg per day.{42572} It inhibits bacterial cell wall synthesis by forming stable acyl enzymes with penicillin-binding proteins, thereby inactivating them.{27720} Formulations containing doripenem have been used in the treatment of bacterial infections.  

 

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Description

A broad-spectrum antibiotic; is active against Gram-negative and Gram-positive bacteria, including S. aureus, S. pneumoniae, E. coli, and K. pneumoniae (MICs = 0.03-0.06, 0.016-0.06, P. aeruginosa respiratory tract infection at 100 mg/kg per day

Formal name: 3-[[(3S,5S)-5S-[[(aminosulfonyl)amino]methyl]-3-pyrrolidinyl]thio]-6S-[(1R)-1-hydroxyethyl]-4R-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid

Synonyms:  S 4661

Molecular weight: 420.5

CAS: 148016-81-3

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Antibiotics|Carbapenems||Product Type|Biochemicals|Antibiotics|Monobactams||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases|Pneumonia

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