A detergent; commonly used for membrane protein structure determination using NMR; has been used to generate membrane mimetic micelles and to characterize pore formation by the influenza M2 transmembrane domain within a synthetic membrane; micelles induce amyloid fibril formation by PrP (110-136); CMC = 1.5 mM

Dodecylphosphocholine – 500 mg

Brand:
Cayman
CAS:
29557-51-5
Storage:
-20
UN-No:
Non-Hazardous - /

Dodecylphosphocholine is a detergent that is commonly used for membrane protein structure determination using NMR.{36909} It has also been used to generate membrane mimetic micelles and to characterize pore formation by the influenza M2 transmembrane domain within a synthetic membrane.{36910} Dodecylphosphocholine micelles induce amyloid fibril formation by the prion protein (PrP) β-strand (PrP (110-136)).{36911} Dodecylphosphocholine has a critical micelle concentration (CMC) of approximately 1.5 mM.  

 

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SKU: 25629 - 500 mg Category:

Description

A detergent; commonly used for membrane protein structure determination using NMR; has been used to generate membrane mimetic micelles and to characterize pore formation by the influenza M2 transmembrane domain within a synthetic membrane; micelles induce amyloid fibril formation by PrP (110-136); CMC = 1.5 mM

Formal name: 2-[[(dodecyloxy)hydroxyphosphinyl]oxy]-N,N,N-trimethyl-ethanaminium, inner salt

Synonyms:  n-Dodecylphosphocholine

Molecular weight: 351.5

CAS: 29557-51-5

Purity: ≥95%

Formulation: A crystalline solid

Application|Sample Preparation||Product Type|Biochemicals|Lab Reagents|Detergents

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