An internal standard for the quantification of docetaxel

Docetaxel-d9 – 500 µg

Brand:
Cayman
CAS:
940867-25-4
Storage:
-20
UN-No:
Non-Hazardous - /

Docetaxel-d9 is intended for use as an internal standard for the quantification of docetaxel (Item No. 11637) by GC- or LC-MS. Docetaxel is a semisynthetic analog of paclitaxel (Item No. 10461) that inhibits microtubule disassembly (IC50 = 0.2 μM) and inhibits cell replication (IC50 = 0.13 μM).{20977} It has proven more effective than taxol in preventing the proliferation of cancer cells.{20977,20979} Docetaxel has potential applications in breast cancer and hormone-refractory prostate cancer.{20980,20978}  

 

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Description

An internal standard for the quantification of docetaxel

Formal name: (αR,βS)-β-[[(1,1-dimethylethoxy)carbonyl]amino]-α-hydroxy-benzenepropanoic acid, β-[[[1,1-di(methyl-d3)ethoxy-2,2,2-d3]carbonyl]amino]-α-hydroxy-12b-(acetyloxy)-12-(benzoyloxy)-2aR,3,4S,4aS,5,6R,9S,10,11S,12S,12aR,12bS-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester

Synonyms:  Taxotel-d9

Molecular weight: 816.9

CAS: 940867-25-4

Purity: ≥98% Docetaxel

Formulation: A solid

Application|Mass Spectrometry||Product Type|Biochemicals|Analytical Standards||Product Type|Biochemicals|Isotopically Labeled Standards|Deuterium||Research Area|Cancer||Research Area|Cell Biology|Cytoskeleton & Motor Proteins

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