Cayman's DNA/RNA Oxidative Damage (Clone 7E6.9) ELISA Kit is a competitive assay that can be used to measure both 8-hydroxy-2'-deoxyguanosine and 8-hydroxyguanosine. This kit has been validated for use in urine

DNA/RNA Oxidative Damage (Clone 7E6.9) ELISA Kit – 480 solid wells

Brand:
Cayman
Storage:
-20

DNA and RNA are damaged by oxidation during aging and in a variety of disease states including cancer.{22083,22087,22086} Guanine is the base is most prone to oxidation, and the repair processes initiated to correct the damage release multiple oxidized guanine species into the urine, including 8-hydroxyguanosine (8-OHG), 8-hydroxy-2’-deoxyguanosine (8-OHdG), and 8-hydroxyguanine. Some commercial vendors offer immunoassays that detect only 8-OHdG. Cayman’s DNA/RNA Oxidative Damage (Clone 7E6.9) ELISA Kit is a competitive assay that can be used to measure both 8-OHdG and 8-OHG. Since the antibody used in the assay recognizes damaged nucleic acid species other than 8-OHdG, the value obtained with our assay will be higher than that obtained by competitor ELISAs or by LC/MS analysis that measure a single species. As such, caution is recommended when comparing results obtained from this kit to those obtained by other methods.  

 

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SKU: 501130 - 480 solid wells Category:

Description

Cayman’s DNA/RNA Oxidative Damage (Clone 7E6.9) ELISA Kit is a competitive assay that can be used to measure both 8-hydroxy-2′-deoxyguanosine and 8-hydroxyguanosine. This kit has been validated for use in urine, but other sample types may be used. The assay has a range from 0.15-20 ng/ml and a sensitivity (80% B/B0) of approximately 0.45 ng/ml.

Formulation:

Formal name:

Synonyms:  8-OHG|8-Hydroxyguanosine|DNA/RNA Oxidative Damage (Clone 7E6.9) EIA Kit

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Imunogen:

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Purity:

Origin: Animal/Bovine|Animal/Eel|Animal/Mouse

Application|ELISA||Product Type|Assay Kits|ELISA||Research Area|Cancer|DNA Damage and Repair||Research Area|Oxidative Stress & Reactive Species|DNA/RNA Oxidative Damage

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