A natural inhibitor of exportin 1

D,L-1′-Acetoxychavicol Acetate – 1 mg

Brand:
Cayman
CAS:
52946-22-2
Storage:
-20
UN-No:
Non-Hazardous - /

D,L-1′-Acetoxychavicol acetate is a natural compound first isolated from the rhizomes of ginger-like plants. It has a wide array of cellular effects that may be largely explained by its ability to inhibit exportin 1 and prevent the export of proteins from the nucleus.{31360,31361} In this way, D,L-1′-acetoxychavicol acetate reduces several intracellular signaling pathways, including NF-κB, impacting inflammation, cancer, viral replication, and other processes.{31359,31361,31362}  

 

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Description

A natural inhibitor of exportin 1, preventing the export of proteins from the nucleus; reduces several intracellular signaling pathways, including NF-κB, impacting inflammation, cancer, viral replication, and other processes

Formal name: (αS)-4-(acetyloxy)-α-ethenyl-benzenemethanol, acetate

Synonyms:  1′-Acetoxychavicol Acetate|ACA|Galangal Acetate

Molecular weight: 234.3

CAS: 52946-22-2

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Antivirals||Product Type|Biochemicals|Natural Products||Product Type|Biochemicals|Small Molecule Inhibitors|MMPs||Product Type|Biochemicals|Small Molecule Inhibitors|TNF-α/NF-κB Signaling||Research Area|Cancer||Research Area|Cell Biology|Cell Signaling|NF-κB Signaling||Research Area|Epigenetics, Transcription, & Translation|Transcription Factors||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Viral Diseases

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