A macrolide antibiotic and prodrug of erythromycylamine that has outstanding activity against Campylobacter

Dirithromycin – 250 mg

Brand:
Cayman
CAS:
62013-04-1
Storage:
-20
UN-No:
Non-Hazardous - /

Dirithromycin is a macrolide antibiotic. It is a prodrug of erythromycylamine (Item No. 28098) that has outstanding activity against Campylobacter.{31455} Dirithromycin is a group 3 agent with respect to its interaction with the cytochrome P450 (CYP) isoform 3A4, as it interferes poorly with CYP3A4 in vitro and generally does not alter drug metabolism in vivo.{22760}  

 

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Description

A macrolide antibiotic and prodrug of erythromycylamine that has outstanding activity against Campylobacter

Formal name: (1R,2R,3R,6R,7S,8S,9R,10R,12R,13S,15R,17S)-7-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-3-ethyl-2,10-dihydroxy-15-[(2-methoxyethoxy)methyl]-2,6,8,10,12,17-hexamethyl-9-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-4,16-dioxa-14-azabicyclo[11.3.1]heptadecan-5-one

Synonyms:  Antibiotic AS-E 136|LY237216

Molecular weight: 835.1

CAS: 62013-04-1

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Antibiotics|Macrolides||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases

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