A bipyridylium herbicide; acts as an electron acceptor in the electron transport chain and is reoxidized by molecular oxygen

Diquat (bromide) – 10 mg

Brand:
Cayman
CAS:
85-00-7
Storage:
-20
UN-No:
- 2811 / 6.1

Diquat is a bipyridylium herbicide that, as a stable radical, acts as an electron acceptor in the electron transport chain and is reoxidized by molecular oxygen, producing reactive oxygen species (ROS).{37559} Diquat administration has been used to induce oxidative stress in vitro and in animal models.{37560,37561,37562} It increases the production of ROS and decreases the mitochondrial membrane potential in mitochondria isolated from porcine intestine leading to mitophagy when administered at a dose of 100 mg/kg.{37560} Formulations containing diquat have been used in agriculture for crop desiccation and defoliation.  

 

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Description

A bipyridylium herbicide; acts as an electron acceptor in the electron transport chain and is reoxidized by molecular oxygen, producing ROS; has been used to induce oxidative stress in vitro and in animal models; increases the production of ROS and decreases the mitochondrial membrane potential in mitochondria isolated from porcine intestine leading to mitophagy at 100 mg/kg,

Formal name: 6,7-dihydro-dipyrido[1,2-a:2′,1′-c]pyrazinediium, dibromide

Synonyms: 

Molecular weight: 344

CAS: 85-00-7

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Pesticides|Herbicides||Research Area|Cell Biology|Mitochondrial Biology||Research Area|Oxidative Stress & Reactive Species|Reactive Oxygen||Research Area|Toxicology|Cell Health & Viability|Mitochondrial (dys)Function||Research Area|Toxicology|Environmental|Agriculture

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