A cationic amphipathic lipid; DDA liposomes containing an Ag85B-ESAT-6 antigen induce antigen deposition at the injection site in mice; has been used in the study of lipid bilayer dynamics

Dimethyldioctadecylammonium (bromide) – 50 g

Brand:
Cayman
CAS:
3700-67-2
Storage:
-20
UN-No:
Non-Hazardous - /

Dimethyldioctadecylammonium (DDA) is a cationic amphipathic lipid.{36982,36983} DDA liposomes containing an Ag85B-ESAT-6 antigen induce antigen deposition at an intramuscular or subcutaneous injection site in mice, increasing immune cell exposure to the antigen.{36984} In a guinea pig model of M. tuberculosis infection, spleen bacterial load is reduced and lung and spleen lesion numbers are decreased when the mycobacterial lipid antigens Ac2SGL and PIM2 are administered in liposomes comprised of DDA and a synthetic analog of the mycobacterial cord factor trehalose 6,6-dibehenate (TDB).{36983} DDA has also been used in the study of lipid bilayer dynamics.{36985}  

 

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SKU: 26120 - 50 g Category:

Description

A cationic amphipathic lipid; DDA liposomes containing an Ag85B-ESAT-6 antigen induce antigen deposition at the injection site in mice; has been used in the study of lipid bilayer dynamics

Formal name: N,N-dimethyl-N-octadecyl-1-octadecanaminium, monobromide

Synonyms:  DDA|DODAB

Molecular weight: 631

CAS: 3700-67-2

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Lipids|Hydrocarbons||Research Area|Cell Biology||Research Area|Immunology & Inflammation|Adaptive Immunity||Research Area|Immunology & Inflammation|Innate Immunity||Research Area|Infectious Disease|Bacterial Diseases|Tuberculosis

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