A derivative of curcurmin with anti-inflammatory and antioxidant activities; inhibits mitogen-induced proliferation of CD4+ T cells

Dimethoxycurcumin – 1 mg

Brand:
Cayman
CAS:
160096-59-3
Storage:
-20
UN-No:
Non-Hazardous - /

Dimethoxycurcumin is a derivative of curcumin (Item No. 81025) that has anti-inflammatory and antioxidant activities.{53899,53900,53901} It inhibits mitogen-induced proliferation of CD4+ T cells, CD8+ T cells, and B cells, as well as secretion of IL-2, IL-4, IL-6, and IFN-γ induced by concanavalin A (Item No. 14951) in isolated human lymphocytes when used at concentrations ranging from 1 to 10 µM.{53899} Dimethoxycurcumin (1-10 µM) inhibits LPS-induced nitric oxide (NO) production and expression of inducible nitric oxide synthase (iNOS) in RAW 264.7 cells.{53900} It inhibits hemolysis of isolated human red blood cells (RBCs) induced by AAPH (Item No. 82235) when used at a concentration of 10 µM.{53901}  

 

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SKU: 10009986 - 1 mg Category:

Description

A derivative of curcurmin with anti-inflammatory and antioxidant activities; inhibits mitogen-induced proliferation of CD4+ T cells, CD8+ T cells, and B cells, as well as concanavalin A-induced secretion of IL-2, IL-4, IL-6, and IFN-γ in isolated human lymphocytes from 1-10 µM; inhibits LPS-induced NO production and expression of iNOS in RAW 264.7 cells from 1-10 µM; inhibits AAPH-induced hemolysis of isolated human RBCs at 10 µM

Formal name: 1,7-bis(3,4-dimethoxyphenyl)-1,6-heptadiene-3,5-dione

Synonyms:  Di-O-methylcurcumin

Molecular weight: 396.4

CAS: 160096-59-3

Purity: ≥90%

Formulation: A crystalline solid

Product Type|Biochemicals|Ox Stress Reagents|Antioxidants||Research Area|Cardiovascular System|Blood|Erythrocytes & Hemoglobin||Research Area|Cell Biology|Cell Signaling|Nitric Oxide Signaling||Research Area|Immunology & Inflammation|Adaptive Immunity||Research Area|Immunology & Inflammation|Innate Immunity||Research Area|Oxidative Stress & Reactive Species|Antioxidant Activity||Research Area|Oxidative Stress & Reactive Species|Reactive Nitrogen|iNOS

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