An organophosphate pesticide; acaricidal against Kanzawa spider mites (LC50 = 7 ppm in an aqueous suspension); inhibits purified Kanzawa spider mite AChE (IC50 = 3.3-5.2 nM); reduces motility and viability and induces abnormal morphology in rat sperm from 50-200 μM; increases MDA production and reduces SOD

Dimethoate – 50 mg

Brand:
Cayman
CAS:
60-51-5
Storage:
-20
UN-No:
Non-Hazardous - /

Dimethoate is an organophosphate pesticide.{42384} It is acaricidal against Kanzawa spider mites (LC50 = 7 ppm in an aqueous suspension) and inhibits purified Kanzawa spider mite acetylcholinesterase (AChE; IC50 = 3.3-5.2 nM). Dimethoate (50-200 μM) reduces motility and viability and induces abnormal morphology of rat sperm.{42385} It also increases production of malondialdehyde (MDA) and reduces superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (Gpx) activities in rat epididymal sperm. In vivo, dimethoate (28 mg/kg per day) decreases sperm count, motility, and viability and increases the percentage of morphologically abnormal sperm in rats.{42386} Dimethoate also induces formation of carcinomas in the adrenal, thyroid, and pituitary glands of male and female rats as well as testicular atrophy, chronic renal disease, polyarteritis, and parathyroid hyperplasia in male rats.{42387}  

 

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SKU: 24246 - 50 mg Category:

Description

An organophosphate pesticide; acaricidal against Kanzawa spider mites (LC50 = 7 ppm in an aqueous suspension); inhibits purified Kanzawa spider mite AChE (IC50 = 3.3-5.2 nM); reduces motility and viability and induces abnormal morphology in rat sperm from 50-200 μM; increases MDA production and reduces SOD, CAT, and Gpx activities in rat epididymal sperm; decreases sperm count, motility, and viability and increases the percentage of morphologically abnormal sperm in rats at 28 mg/kg per day; induces formation of carcinomas in the adrenal, thyroid, and pituitary glands of male and female rats as well as testicular atrophy, chronic renal disease, polyarteritis, and parathyroid hyperplasia in male rats,

Formal name: phosphorodithioic acid, O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] ester

Synonyms:  CL 12,880|ENT 24,650

Molecular weight: 229.3

CAS: 60-51-5

Purity: ≥98%

Formulation: A solid

Product Type|Biochemicals|Pesticides|Acaricides||Product Type|Biochemicals|Small Molecule Inhibitors|Acetylcholine Turnover||Product Type|Biochemicals|Small Molecule Inhibitors|Peptidases & Proteases||Research Area|Cancer||Research Area|Endocrinology & Metabolism|Reproductive Biology||Research Area|Toxicology|Cell Health & Viability||Research Area|Toxicology|Environmental|Agriculture

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