Description
A flavanonol with diverse biological activities; scavenges DPPH radicals (IC50 = 0.235 μg/ml) and decreases AAPH-induced ROS generation in human erythrocytes (6 μg/ml); dose-dependently decreases proliferation and increases apoptosis in human liver carcinoma HepG2 cells; decreases tumor volume by 43.5% in a mouse xenograft model of HepG2 cells (500 mg/kg per day); binds to GABAA receptors in rat cortical membrane reparations (IC50 = 4.36 μM); dose-dependently reduces LORR in ethanol-intoxicated rats; improves cognitive deficits in a mouse model of Alzheimer’s disease (2 mg/kg for three months)
Formal name: (2R,3R)-2,3-dihydro-3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-1-benzopyran-4-one
Synonyms: (+)-Dihydromyricetin
Molecular weight: 320.3
CAS: 27200-12-0
Purity: ≥98%
Formulation: A crystalline solid
Product Type|Biochemicals|Natural Products|Flavonoids||Product Type|Biochemicals|Ox Stress Reagents|Antioxidants||Research Area|Cancer|Cell Death|Apoptosis||Research Area|Neuroscience|Behavioral Neuroscience|Addiction Research||Research Area|Neuroscience|Behavioral Neuroscience|Learning & Memory||Research Area|Neuroscience|Neurodegenerative Disorders|Alzheimer’s Disease||Research Area|Oxidative Stress & Reactive Species|Antioxidant Activity||Research Area|Oxidative Stress & Reactive Species|Reactive Oxygen|Non-enzymatic
