A fluorescent dye to monitor superoxide production; ex/em = 490/590 nm; has been used to detect ROS and intracellular superoxide in vitro

Dihydroethidium – 5 mg

Brand:
Cayman
CAS:
104821-25-2
Storage:
-20
UN-No:
Non-Hazardous - /

Dihydroethidium is a cell-permeable blue fluorescent dye that upon entering cells interacts with superoxide to form oxyethidium, which intercalates with nucleic acids and emits a red fluorescence detectable qualitatively by fluorescent microscopy or quantitatively by HPLC.{21946} It displays excitation/emission spectra of 490/590 nm.{40467} This selective and sensitive probe has been used to detect reactive oxygen species during the phagocytic respiratory burst and for the detection of intracellular superoxide in cultured cells.{21947,21948,21944}  

 

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Description

A fluorescent dye to monitor superoxide production; ex/em = 490/590 nm; has been used to detect ROS and intracellular superoxide in vitro

Formal name: 5-ethyl-5,6-dihydro-6-phenyl-3,8-phenanthridinediamine

Synonyms:  Hydroethidine|PD-MY 003

Molecular weight: 315.4

CAS: 104821-25-2

Purity: ≥98%

Formulation: A crystalline solid

Application|Fluorescence||Product Type|Biochemicals|Labeling & Detection|Fluorescent Probes||Product Type|Biochemicals|Labeling & Detection|Reactive Probes||Research Area|Oxidative Stress & Reactive Species|Reactive Oxygen

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