An alkaloid with diverse biological activities; inhibits contraction of isolated rat vas deferens induced by norepinephrine (pA2 = 7.88); reduces blood pressure in a rat model of norepinephrine-induced hypertension and increases blood pressure in hypotensive rats from 0.1-100 µg/kg

Dihydroergocristine (mesylate) – 100 mg

Brand:
Cayman
CAS:
24730-10-7
Storage:
-20
UN-No:
Non-Hazardous - /

Dihydroergocristine is an alkaloid with diverse biological activities.{48820,48821,48822,48823} It inhibits contraction of isolated rat vas deferens induced by norepinephrine (pA2 = 7.88) but not calcium.{48820} Dihydroergocristine (0.1-100 µg/kg, i.v.) reduces blood pressure in a rat model of norepinephrine-induced hypertension and increases blood pressure in hypotensive rats.{48821} It reduces aqueous humor production and intraocular pressure in a rabbit model of α-chymotrypsin-induced ocular hypertension.{48822} Dihydroergocristine also reduces hypermotility induced by ethanol in mice.{48823}  

 

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SKU: 29492 - 100 mg Category:

Description

An alkaloid with diverse biological activities; inhibits contraction of isolated rat vas deferens induced by norepinephrine (pA2 = 7.88); reduces blood pressure in a rat model of norepinephrine-induced hypertension and increases blood pressure in hypotensive rats from 0.1-100 µg/kg, i.v.; reduces aqueous humor production and intraocular pressure in a rabbit model of α-chymotrypsin-induced ocular hypertension; reduces hypermotility induced by ethanol in mice

Formal name: 9,10α-dihydro-12′-hydroxy-2′-(1-methylethyl)-5′α-(phenylmethyl)-ergotaman-3′,6′,18-trione, monomethanesulfonate

Synonyms: 

Molecular weight: 707.8

CAS: 24730-10-7

Purity: ≥95%

Formulation: A solid

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