A potential impurity found in commercial montelukast preparations

Dihydro Montelukast – 500 µg

Brand:
Cayman
CAS:
142147-67-9
Storage:
-20
UN-No:
Non-Hazardous - /

Dihydro montelukast is a potential impurity found in commercial montelukast preparations. Montelukast (sodium salt) (Item No. 10008318) is a potent and selective cysteinyl leukotriene 1 (CysLT1) receptor antagonist. Formulations containing montelukast are used for the treatment of asthma as well as for the symptoms associated with allergic rhinitis.{6475,6685,14084,14106}  

 

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Description

A potential impurity found in commercial montelukast preparations,

Formal name: 1-[[[(1R)-1-[3-[2-(7-chloro-2-quinolinyl)ethyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]-cyclopropaneacetic acid

Synonyms: 

Molecular weight: 588.2

CAS: 142147-67-9

Purity: ≥98%

Formulation: A solid

Application||Product Type|Biochemicals|Pharmaceutical Impurities||Product Type|Biochemicals|Receptor Pharmacology|Antagonists||Research Area|Immunology & Inflammation|Allergy||Research Area|Immunology & Inflammation|Pulmonary Diseases|Asthma||Research Area|Lipid Biochemistry|Lipoxygenase Pathways

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