Description
A triazole antifungal; inhibits ergosterol biosynthesis via inhibition of the cytochrome P450-dependent 14α-demethylation of lanosterol; inhibits the growth of F. graminearum isolates in vitro (EC50s = 1.69-19.6 mg/L for mycelial growth); inhibits growth of A. sonali, F. fulva, B. cinerea, and R. solani (EC50s = 0.131, 0.069, 0.297, and 0.252 mg/L, respectively); reduces germtube growth of A. caricae (EC50 = 2 ppm); lethal to zebrafish embryos, larvae, and adults (LC50s = 2.34, 1.17, and 1.45 mg/L, respectively); induces pericardial and yolk sac edema in zebrafish embryos, body blackening and slowed heart rate in larvae, and decreased body weight and length in adults,
Formal name: 1-[[2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-methyl-1,3-dioxolan-2-yl]methyl]-1H-1,2,4-triazole
Synonyms: CGA 169374
Molecular weight: 406.3
CAS: 119446-68-3
Purity: ≥95%
Formulation: A solid
Product Type|Biochemicals|Pesticides|Fungicides||Product Type|Biochemicals|Small Molecule Inhibitors|Cytochrome P450||Product Type|Biochemicals|Small Molecule Inhibitors|Sterol Biosynthesis||Research Area|Cell Biology||Research Area|Plant Biology||Research Area|Toxicology|Cell Health & Viability||Research Area|Toxicology|Drug Metabolism|Cytochrome P450||Research Area|Toxicology|Environmental
