A potent inhibitor of monoamine reuptake

Diclofensine (hydrochloride) – 5 mg

Brand:
Cayman
CAS:
34041-84-4
Storage:
-20
UN-No:
Non-Hazardous - /

Diclofensine is a potent inhibitor of monoamine reuptake, blocking the uptake of dopamine, noradrenaline, and serotonin by rat brain synaptosomes with IC50 values of 0.74, 2.3, and 3.7 nM, respectively.{25265} While it has applications as an antidepressant, diclofensine increases locomotor activity, decreases food intake, and has abuse potential.{25264,25263,25268,25267} This product is intended for research and forensic applications.  

 

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Description

A potent inhibitor of monoamine reuptake, blocking the uptake of dopamine, noradrenaline, and serotonin by rat brain synaptosomes with IC50 values of 0.74, 2.3, and 3.7 nM, respectively

Formal name: 4-​(3,​4-​dichlorophenyl)​-​1,​2,​3,​4-​tetrahydro-​7-​methoxy-​2-​methyl-​isoquinoline, monohydrochloride

Synonyms:  Ro 8-4650

Molecular weight: 358.7

CAS: 34041-84-4

Purity: ≥98%

Formulation: A crystalline solid

Application|Mass Spectrometry||Product Type|Biochemicals|Drugs of Abuse||Research Area|Forensic Chemistry & Toxicology|Antidepressants||Research Area|Forensic Chemistry & Toxicology|Stimulants

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