Intended for use as an internal standard for the quantification of diclofenac by GC- or LC-MS

Diclofenac-d4 – 500 µg

Brand:
Cayman
CAS:
153466-65-0
Storage:
22
UN-No:
De Minimis - 2811 / 6.1

Diclofenac-d4 contains four deuterium atoms on the benzene ring. It is intended for use as an internal standard for the quantification of diclofenac (Item No. 70680) by GC- or LC-mass spectrometry. Diclofenac is a non-selective COX inhibitor.{1791,1286,1364} It inhibits human COX-1 and -2 with IC50 values of 0.9-2.7 and 1.5-20 µM, respectively.{1791,1286} Diclofenac inhibits ovine COX-1 and -2 with IC50 values of 60 and 220 nM, respectively.{1364}  

 

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Description

Intended for use as an internal standard for the quantification of diclofenac by GC- or LC-MS

Formal name: 6-[(2,6-dichlorophenyl)amino]-benzene-2,3,4,5-d4-acetic acid

Synonyms:  Benfofen-d4|Ecofenac-d4|Voltaren-d4

Molecular weight: 300.2

CAS: 153466-65-0

Purity: ≥99%

Formulation: A solid

Application|Mass Spectrometry||Product Type|Biochemicals|Analytical Standards||Product Type|Biochemicals|Isotopically Labeled Standards|Deuterium||Product Type|Biochemicals|Small Molecule Inhibitors|Cyclooxygenases||Research Area|Immunology & Inflammation|Arthritis (Non-autoimmune)||Research Area|Immunology & Inflammation|Autoimmunity|Rheumatoid Arthritis||Research Area|Immunology & Inflammation|Inflammatory Lipid Mediators|Prostaglandins||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway

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