An organosulfur compound; active against the bacteria S. aureus and MRSA (MICs = 0.5 and 2 mg/L

Diallyl Tetrasulfide – 5 mg

Brand:
Cayman
CAS:
2444-49-7
Storage:
-20
UN-No:
Non-Hazardous - /

Diallyl tetrasulfide is an organosulfur compound that has been found in A. sativum and has diverse biological activities, including antimicrobial, antioxidant, and anticancer properties.{46565,46562,46563,46564} It is active against the bacteria S. aureus and methicillin-resistant S. aureus (MRSA; MICs = 0.5 and 2 mg/L, respectively), as well as the fungi C. albicans, C. krusei, C. glabrata, A. niger, A. flavus, and A. fumigatus (MICs = 0.5, 4, 2, 1, 2, and 4 mg/L, respectively).{46565}It reduces cadmium-induced increases in hepatic levels of thiobarbituric acid reactive substances (TBARS) and increases cadmium-induced decreases in the hepatic activity of superoxide dismutase (SOD1), catalase, GST, and glucose-6-phosphate dehydrogenase (G6PDH) in rats when administered at a dose of 40 mg/kg.{46562} Diallyl tetrasulfide is cytotoxic to MCF-7 breast cancer cells (IC50 = 92 µM) and reduces tumor growth in a BGC-823 mouse xenograft model when administered at doses of 20, 30, and 40 mg/kg for 32 days.{46563,46564}  

 

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SKU: 29328 - 5 mg Category:

Description

An organosulfur compound; active against the bacteria S. aureus and MRSA (MICs = 0.5 and 2 mg/L, respectively), as well as C. albicans, C. krusei, C. glabrata, A. niger, A. flavus, and A. fumigatus (MICs = 0.5, 4, 2, 1, 2, and 4 mg/L, respectively); reduces cadmium-induced increases in hepatic levels of TBARS and increases cadmium-induced decreases in the hepatic activity of SOD1, catalase, GST, and G6PDH in rats at 40 mg/kg; cytotoxic to MCF-7 breast cancer cells (IC50 = 92 µM) and reduces tumor growth in a BGC-823 mouse xenograft model at 20, 30, and 40 mg/kg for 32 days

Formal name: di-2-propen-1-yl tetrasulfide

Synonyms:  ICD-1585

Molecular weight: 210.4

CAS: 2444-49-7

Purity: ≥90%

Formulation: An oil

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