A potent

diacetoxy Scirpenol – 1 mg

Brand:
Cayman
CAS:
2270-40-8
Storage:
-20
UN-No:
De Minimis - 3462 / 6.1

diacetoxy Scirpenol (DAS) is a potent, trichothecene mycotoxin produced by certain Fusarium strains, which play an important role as plant pathogens, causing a wide range of diseases.{20564} It is toxic to fungi, plants, animals, and various mammalian cell cultures, inhibiting de novo protein synthesis.{20563} In a biological activity assay, DAS was shown to inhibit expression of the Arabidopsis MAMP-responsive reporter gene WRKY29p::GUS with an IC50 value of 50 nM, thereby suppressing a rapid cell death immune response important for plant defense.{20565}  

 

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SKU: 11427 - 1 mg Category:

Description

A potent, trichothecene mycotoxin produced by certain Fusarium strains that is toxic to fungi, plants, animals, and various mammalian tissue cultures via inhibition de novo protein synthesis

Formal name: (3α,4β)-12,13-epoxy-4,15-diacetate-trichothec-9-ene-3,4,15-triol

Synonyms:  Anguidin|DAS|NSC 141537|NSC 177378|Scirpenetriol 4,15-diacetate

Molecular weight: 366.4

CAS: 2270-40-8

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Toxins|Mycotoxins||Research Area|Plant Biology|Phytotoxins||Research Area|Toxicology|Cell Health & Viability

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