An anthelmintic spiroindole that acts as a nicotinic acetylcholine receptor antagonist

Derquantel – 5 mg

Brand:
Cayman
CAS:
187865-22-1
Storage:
-20
UN-No:
Non-Hazardous - /

Derquantel is an anthelmintic spiroindole that acts as a nicotinic acetylcholine receptor antagonist, causing flaccid paralysis and expulsion of nematodes.{31084} A combination of derquantel and the macrocyclic lactone, abamectin (Item No. 19201), has been found to have synergistic anthelmintic effects against gastrointestinal nematode parasites in sheep.{31083}  

 

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Description

An anthelmintic spiroindole that acts as a nicotinic acetylcholine receptor antagonist, causing flaccid paralysis and expulsion of nematodes

Formal name: (1’R,5’aS,7’R,8’aS,9’aR)-2′,3′,8’a,9,9′,10-hexahydro-1′-hydroxy-1′,4,4,8′,8′,11′-hexamethyl-spiro[4H,8H-[1,4]dioxepino[2,3-g]indole-8,7′(8’H)-[5H,6H-5a,9a](iminomethano)[1H]cyclopent[f]indolizin]-10′-one

Synonyms:  2-deoxy-Paraherquamide|PF-00520904|PNU 141962

Molecular weight: 479.6

CAS: 187865-22-1

Purity: ≥98%

Formulation: A solid

Product Type|Biochemicals|Antiparasitics|Anthelmintics||Product Type|Biochemicals|Ion Channel Modulation|Blockers||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Parasitic Diseases

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