An NSAID and selective COX-2 inhibitor (IC50s = 0.63 and 23 μM for COX-2 and COX-1

Deracoxib – 100 mg

Brand:
Cayman
CAS:
169590-41-4
Storage:
-20
UN-No:
Non-Hazardous - /

Deracoxib is a non-steroidal anti-inflammatory drug (NSAID) and selective inhibitor of COX-2 (IC50s = 0.63 and 23 μM for COX-2 and COX-1, respectively).{11869} In vivo, deracoxib (0.3-10 mg/kg) increases weight bearing and decreases lameness and joint effusion in a canine model of urate crystal-induced intraarticular synovitis.{48433} Deracoxib induces less lesion formation in the gastric mucosa of healthy canines than aspirin (Item No. 70260) when administered at a dose of 1.5 mg/kg.{48434} Formulations containing deracoxib have been used in the treatment of pain associated with canine osteoarthritis.  

 

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SKU: 27371 - 100 mg Category:

Description

An NSAID and selective COX-2 inhibitor (IC50s = 0.63 and 23 μM for COX-2 and COX-1, respectively); increases weight bearing and decreases lameness and joint effusion in a canine model of urate crystal-induced intraarticular synovitis; induces less lesion formation in the gastric mucosa of healthy canines than aspirin at 1.5 mg/kg

Formal name: 4-[3-(difluoromethyl)-5-(3-fluoro-4-methoxyphenyl)-1H-pyrazol-1-yl]-benzenesulfonamide

Synonyms:  SC-59046

Molecular weight: 397.4

CAS: 169590-41-4

Purity: ≥98%

Formulation: A solid

Product Type|Biochemicals|Small Molecule Inhibitors|Cyclooxygenases||Research Area|Immunology & Inflammation|Arthritis (Non-autoimmune)||Research Area|Neuroscience|Pain Research

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