A synthetic bile acid and a derivative of cholic acid; increases bile flow by 2.7-fold and decreases biliary levels of phospholipids

Dehydrocholic Acid – 5 g

Brand:
Cayman
CAS:
81-23-2
Storage:
-20
UN-No:
Non-Hazardous - /

Dehydrocholic acid is a synthetic bile acid and a derivative of cholic acid (Item No. 20250).{45632} It increases bile flow by 2.7-fold and decreases biliary levels of phospholipids, cholesterol, and bilirubin in conscious dogs when administered at a dose of 50 mg/kg.{45633} Dehydrocholic acid (1 µmol/min/0.1 kg) increases bile flow by 253% and decreases the secretion rate of phospholipids and cholesterol by 64 and 94%, respectively, in rats when infused intravenously at a dose of 2 µmol/min/0.1 kg.{45634}  

 

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SKU: 29176 - 5 g Category:

Description

A synthetic bile acid and a derivative of cholic acid; increases bile flow by 2.7-fold and decreases biliary levels of phospholipids, cholesterol, and bilirubin in conscious dogs at 50 mg/kg; increases bile flow by 253% at 1 µmol/min/0.1 kg and decreases the secretion rate of phospholipids and cholesterol by 64 and 94%, respectively, in rats when infused intravenously at 2 µmol/min/0.1 kg

Formal name: (5β)-3,7,12-trioxo-cholan-24-oic acid

Synonyms:  3,7,12-Triketocholanic Acid|NSC 8796|Triketocholanoic Acid

Molecular weight: 402.5

CAS: 81-23-2

Purity: ≥95%

Formulation: A crystalline solid

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