Description
An iron chelator that binds to iron in a 3:1 (ligand:iron) ratio and has antioxidant and neuroprotective activities; reduces levels of intracellular iron and inhibits lipid peroxidation in primary rat hepatocytes at 200 and 50 µM, respectively; reduces cholesterol diet-induced increases in the levels of Aβ42, Aβ40, and the phosphorylation of tau and GSK-3β in the rabbit hippocampus at 50 mg/kg
Formal name: 3-hydroxy-1,2-dimethyl-4(1H)-pyridinone
Synonyms: CGP 37391|DN 18001AF
Molecular weight: 139.2
CAS: 30652-11-0
Purity: ≥95%
Formulation: A crystalline solid
Product Type|Biochemicals|Metal Chelators||Product Type|Biochemicals|Ox Stress Reagents|Antioxidants||Research Area|Cell Biology|Cell Death|Ferroptosis||Research Area|Endocrinology & Metabolism||Research Area|Neuroscience|Neurodegenerative Disorders|Alzheimer’s Disease||Research Area|Oxidative Stress & Reactive Species|Antioxidant Activity||Research Area|Oxidative Stress & Reactive Species|Lipid Peroxidation
