A derivative of anisomycin; inhibits the growth of the P. falciparum strains K1 and T9-96 in vitro (IC50s = 40.29 and 33.57 μM

Deacetylanisomycin – 25 mg

Brand:
Cayman
CAS:
27958-06-1
Storage:
-20
UN-No:
Non-Hazardous - /

Deacetylanisomycin is a derivative of the protein and DNA synthesis inhibitor anisomycin (Item No. 11308) with antimalarial and anticancer activity.{42191,47372} It inhibits the growth of the P. falciparum strains K1 and T9-96 in vitro (IC50s = 40.29 and 33.57 μM, respectively).{42191} Deacetylanisomycin is cytotoxic to LU99 lung carcinoma and MCF-7 breast cancer cells (IC50s = 23 and 34 μM, respectively). It has been used as a negative control for assessment of protein synthesis inhibitor activity in molluscan neurons.{47373}  

 

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Description

A derivative of anisomycin; inhibits the growth of the P. falciparum strains K1 and T9-96 in vitro (IC50s = 40.29 and 33.57 μM, respectively); cytotoxic to LU99 lung carcinoma and MCF-7 breast cancer cells (IC50s = 23 and 34 μM, respectively); been used as a negative control for assessment of protein synthesis inhibitor activity in molluscan neurons

Formal name: (2R,3S,4S)-2-[(4-methoxyphenyl)methyl]-3,4-pyrrolidinediol

Synonyms:  (−)-Deacetylanisomycin|SA 3097D1

Molecular weight: 223.3

CAS: 27958-06-1

Purity: ≥99%

Formulation: A solid

Product Type|Biochemicals|Antiparasitics|Antiprotozoals||Research Area|Cancer|Cell Death||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Parasitic Diseases|Malaria

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