An anti-inflammatory

Dapsone – 50 g

Brand:
Cayman
CAS:
80-08-0
Storage:
-20
UN-No:
Non-Hazardous - /

Dapsone is an anti-inflammatory, antimalarial, and antibacterial compound.{28213} In vivo, dapsone (34 μg/animal per day) reduces epidermal hyperproliferation and epithelial thickness in the esophagus in a mouse model of proliferative dermatitis.{38501} It reduces lipid peroxidation, myeloperoxidase activity, and cellular apoptosis in the striatum of rats following ischemia and reperfusion injury.{38502} Dapsone reduces growth of M. leprae in the footpad of mice (MIC = 0.01-0.03 μg/ml in sera) and induces clearance of P. knowlesi infections in macaques.{38503,38504} It also reduces the number of P. gallinaceum sporozoites in a mosquito population allowed to feed on dapsone-treated chicks.{38504} Formulations containing dapsone have been used in the treatment of malaria, acne, dermatitis, and leprosy.  

 

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SKU: 23743 - 50 g Category:

Description

An anti-inflammatory, antimalarial, and antibacterial compound; reduces epidermal hyperproliferation and epithelial thickness in the esophagus in a mouse model of proliferative dermatitis when administered at a dose of 34 μg/animal per day; reduces lipid peroxidation, myeloperoxidase activity, and cellular apoptosis in the striatum of rats following ischemia and reperfusion injury; reduces growth of M. leprae in the footpad of mice (MIC = 0.01-0.03 μg/ml in sera); induces clearance of P. knowlesi infections in macaques; reduces the number of P. gallinaceum sporozoites in a mosquito population allowed to feed on dapsone-treated chicks,

Formal name: 4,4′-sulfonylbis-benzenamine

Synonyms:  4,4′-Diaminodiphenyl sulfone|NSC 6091

Molecular weight: 248.3

CAS: 80-08-0

Purity: ≥98%

Formulation: A solid

Product Type|Biochemicals|Antibiotics||Product Type|Biochemicals|Antiparasitics|Antiprotozoals||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases|Leprosy||Research Area|Infectious Disease|Parasitic Diseases||Research Area|Neuroscience|Neuroprotection|Ischemia

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