A GlyCer synthetase inhibitor; an inhibitor of MDCK cell growth in vitro (70% reduction at 20 µM); an inhibitor of DNA synthesis at 3 µM

D-threo-PPMP (hydrochloride) – 10 mg

Brand:
Cayman
CAS:
139889-65-9
Storage:
-20
UN-No:
Non-Hazardous - /

D-threo-PPMP is a glucosylceramide (GlyCer) synthetase inhibitor.{28272},{37030} It is the active enanantiomer and enzymatic inhibitory component of the racemic DL-threo-PPMP (Item No. 17236). In MDCK kidney epithelial cells, D-threo-PPMP induces a 70% reduction in cell growth in vitro at 20 µM and significantly inhibits DNA synthesis at 3 µM.{11391} [Matreya, LLC. Catalog No. 1865]  

 

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Description

A GlyCer synthetase inhibitor; an inhibitor of MDCK cell growth in vitro (70% reduction at 20 µM); an inhibitor of DNA synthesis at 3 µM

Formal name: [R-(R*,R*)]-N-[2-hydroxy-1-(4-morpholinylmethyl)-2-phenylethyl]-hexadecanamide, monohydrochloride

Synonyms:  D-threo-1-phenyl-2-Palmitoylamino-3-morpholino-1-propanol

Molecular weight: 511.2

CAS: 139889-65-9

Purity: ≥98%

Formulation: A solid

Product Type|Biochemicals|Small Molecule Inhibitors|Sphingolipid Turnover||Research Area|Epigenetics, Transcription, & Translation|RNA, DNA, & Protein Synthesis||Research Area|Lipid Biochemistry|Sphingolipids

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