Ins(4)P1 is a member of the inositol phosphate (InsP) molecular family that play critical roles as small

D-myo-Inositol-4-phosphate (ammonium salt) – 500 µg

Brand:
Cayman
CAS:
142760-33-6
Storage:
-20
UN-No:
Non-Hazardous - /

D-myo-Inositol-4-phosphate (Ins(4)P1) is a member of the inositol phosphate (InsP) molecular family that play critical roles as small, soluble second messengers in the transmission of cellular signals.{8344,8672} The most studied InsP, Ins(1,4,5)P3, is a second messenger produced in cells by phospholipase C (PLC)-mediated hydrolysis of phosphatidylinositol-4,5-diphosphate.{2429,5714} Binding of Ins(1,4,5)P3 to its receptor on the endoplasmic reticulum results in opening of the calcium channels and an increase in intracellular calcium.{5714,4096} Ins(4)P1 can be formed by dephosphorylation of Ins(1,4)P2 by inositol polyphosphate 1-phosphatase or dephosphorylated to inositol by inositol monophosphatase.{8344}  

 

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Description

Ins(4)P1 is a member of the inositol phosphate (InsP) molecular family that play critical roles as small, soluble second messengers in the transmission of cellular signals.{8344,8672} The most studied InsP, Ins(1,4,5)P3, is a second messenger produced in cells by PLC-mediated hydrolysis of PtdIns-4,5-diphosphate.{2429,5714} Binding of Ins(1,4,5)P3 to its receptor on the endoplasmic reticulum results in opening of the calcium channels and an increase in intracellular calcium.{5714,4096} Ins(4)P1 can be formed by dephosphorylation of Ins(1,4)P2 by inositol polyphosphate 1-phosphatase or dephosphorylated to inositol by inositol monophosphatase.{8344}

Formal name: D-myo-inositol-4-hydrogen phosphate, monoammonium salt

Synonyms:  4-IP1 (ammonium salt)|Ins(4)P1 (ammonium salt)

Molecular weight: 277.2

CAS: 142760-33-6

Purity: ≥98%

Formulation: A lyophilized powder

Product Type|Biochemicals||Research Area|Cell Biology|Cell Signaling||Research Area|Cell Biology|Inositol Phosphates

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