Ins(1

D-myo-Inositol-1,4,5,6-tetraphosphate (sodium salt) – 1 mg

Brand:
Cayman
CAS:
157542-47-7
Storage:
-20
UN-No:
Non-Hazardous - /

D-myo-Inositol-1,4,5,6-tetrahosphate (sodium salt) (Ins(1,4,5,6)-P4) is one of several different inositol oligophosphate isomers implicated in signal transduction. Production of Ins(1,4,5,6)-P4 by intestinal epithelial cells increases approximately 2-14 fold, depending on the strain and incubation time, following infection with Salmonella. D-myo-Inositol-1,4,5,6-tetraphosphate (sodium salt) (Ins(1,4,5,6)-P4) is one of several different inositol oligophosphate isomers implicated in signal transduction. Production of Ins(1,4,5,6)-P4 by intestinal epithelial cells increases approximately 2-14 fold, depending on the strain and incubation time, following infection with Salmonella.{13729} Ins(1,4,5,6)-P4 antagonizes epidermal growth factor (EGF) signalling through the phosphatidylinositol 3-kinase pathway.{13729} Ins(1,4,5,6)-P4 (tested as the D/L racemic mixture) is ~1,000-fold less potent than Ins(1,4,5)-P3 at initiating Ca2+ release when injected into Xenopus oocytes.{13725}  

 

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SKU: 10007783 - 1 mg Category:

Description

Ins(1,4,5,6)-P4 is one of several different inositol oligophosphate isomers implicated in signal transduction. Production of Ins(1,4,5,6)-P4 by intestinal epithelial cells increases approximately 2-14 fold, depending on the strain and incubation time, following infection with Salmonella.{13729} Ins(1,4,5,6)-P4 antagonizes epidermal growth factor (EGF) signalling through the phosphatidylinositol 3-kinase pathway.{13729} Ins(1,4,5,6)-P4 (tested as the D/L racemic mixture) is ~1,000-fold less potent than Ins(1,4,5)-P3 at initiating Ca2+ release when injected into Xenopus oocytes.{13725}

Formal name: D-myo-inositol-1,4,5,6-tetra(hydrogen phosphate), tetrasodium salt

Synonyms:  1,4,5,6-IP4|Ins(1,4,5,6)-P4

Molecular weight: 588

CAS: 157542-47-7

Purity: ≥98%

Formulation: A lyophilized powder

Product Type|Biochemicals||Research Area|Cell Biology|Cell Signaling||Research Area|Cell Biology|Inositol Phosphates||Research Area|Lipid Biochemistry|Glycerophospholipids|Phosphatidyl Inositol Kinases & Phosphatases

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